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Due to the high quality of our formula and its more than proven effectiveness, it is not odd to find numerous and detailed tests on the ingredients these days. Below, we will show you some of them, developed by professionals of the field, on the effectiveness of the ingredients of the exclusive and revolutionary formula of our Procurves pills. |
El Bioperine is a patented new and revolutionary ingredient that considerably improves the absorption of the rest of the ingredients by our body, facilitating the assimilation while speeding and improving the results in an extraordinary way. It is a standardized extract of piperine, the main alkaloid of black pepper, being an extremely pure and safe form of the latter. It is obtained from fruits that come from plants cultivated in the humid regions, rich in Nigrum L. (black pepper). Next, we offer you a chart and some scientific explanations regarding the origin and importance of Bioperine: |
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The subtle yet potent properties of Bioperine® have been measured in several clinical studies with totally healthy volunteers in the U.S. These studies measured the absorption of three distinct categories of products. The categories evaluated with and without Bioperine® were fat-soluble (beta-carotene), water-soluble (vitamin B 6) and a mineral (selenium, in the form of selenomethionine). Gastrointestinal absorption of all the studied nutrients, as measured by amounts present in the blood, increased dramatically when administered with Bioperine® as compared to the control group receiving the nutrient alone. Selenium levels increased by 30%, beta-carotene increased by 60%, and the vitamin B 6 increase was slightly higher than beta-carotene. All studies used Bioperine® in the amount of 5 mg per dose. |
In general, the plants are abundant in the northern, western and northwestern woods of Thailand. The active principles of this plant are located in the interconnected tuberous roots, which look like chains of round-shaped bulbs. The form and shape of the tuberous roots may vary, depending on the environment they grow in. There are 9 species of the Pueraria genus found in Thailand that are very similar. However, the authenticity of Pueraria Mirifica can be clearly verified through the different characteristics of the flower’s stamen and its hairy pod. The tuber enables increasing and accumulating at least 13 natural chemical products, known and classified as Phytoestrogens: miroestrol, daidzein, genistin, genistein, B-sitosterol, stigmasterol, coumestrol, pueraria, compesterol, mirificoumestan, kwakhurin and mirificin. In the East, the belief in the miraculous and rejuvenating properties of Pueraria Mirifica has passed from generation to generation for centuries. The rhizome extract of Pueraria mirifica contains “phytoestrogens " (Hormone from Plant) comprising isoflavones (daidzin, daidzein, genistin, genistein and puerarin) and others such as miroestrol and its derivatives, beta-sitosterol, stigmasterol, coumestrol, puerarin, mirificoumestan, kwakhurin, mirificin, b-sitosterol, alkane alcohol, fat, and sugar. It has been reported that Pueraria mirifica contains estrogenic substance miroestrol, which can be found in the dry rhizome of Pueraria mirifica about 0.002-0.003%. This substance has been proven to be 2 times more effective than human estrogen. The phytoestrogen of Pueraria Mirifica is also high in phytoestrogen, a substance that imitates female estrogen.
A series of studies about breast cell lines and the activity of Pueraria mirifica in vitro have been jointly performed by the Emory University School of Medicine in Atlanta, Georgia, USA, and the Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, Thailand. These studies have shown that Pueraria mirifica root extract (Smith natural products Co Ltd., Bangkok) has potent anti-estrogenic properties against aggressive cell cancer lines in vitro, especially the proliferative estrogen receptor-positive (ER+) breast cancer lines (T47-D, MCF-7, and ZR-75-1) obtained from the MD Anderson Cancer Institute (Texas) and the National Cancer Institute (NCI) at the U.S. National Institutes of Health (NIH). Pueraria mirifica promotes fibroblasts in normal breast cells and inhibits estrogen-dependent breast cancer cells. Unpublished, 2001, Sawatsri, S., Juntayanee, B., Jitpatima, S., Boonnao, P., Kampoo, C., Ayuttaya, N., Wongyai, S. and Sidell, N. According to the study conducted at the School of Medicine, Saint Mariane University, Tokyo, Japan by Kuramoshi, T. and Smitasiri, Y. about the preliminary study of Pueraria mirifica in Japanese females, 50 healthy menstruating volunteer females, ages 20 to 49, were given between 100 to 600 mg orally of Pueraria mirifica root powder daily as capsules for 7 days, two weeks after menstruation. No reports of abnormally heavy, severe, or missed menstruation were recorded.
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Pueraria mirifica (also known as Kwao Krua or Butea Superba) is a botany species found in Thailand and Myanmar. Its tubers are used for the general improvement of the breast because it enlarges the mammary conducts, allowing the stimulation and widening of fat tissues. This results in firmer breast. Besides, it maintains the collagen and develops new skin cells, providing smooth, well-formed beautiful breast.
Phytoestrogens are very important in Procurves Plus because the 100 % natural ingredients that compose it possess very powerful estrogenic properties. Phytoestrogen’s most significant estrogenic properties are the ability to act as endogen estrogens, facilitating the mammary development of the glands. In an early stage of fetal life of the epithelial cells, derived from the epidermis of the area that will later become the areola, proliferate into the underlying mesenchyme. In the human being, 20 or less cords are formed, which develop to become the ducts that are connected to the nipple and open to the surface. They surround the ducts in a network of myeloepithelial cells, destined ultimately to serve in the expulsion of milk. In the later stages of gestation the blind ends of the ducts bud to form alveolar structures and a small amount of secretory activity occurs. The results of this formation in the breast occur past a period of 1 to 7 weeks. Subsequently, with the absence of placental estrogen and progesterone, the breast returns to a resting stage composed by small number of dispersed conducts. Such regression may not be completed until months after the birth. In several species, there is sexual dimorphism in the embryogenesis of the excretory duct system. In human beings, it appears as a histological or functional difference in the breasts of girls and boys before puberty. Shortly before human menarche, with increased secretion of ovarian estrogen, lengthening and branching of the ducts begin in the female breast, along with the terminal ends and the increasing formation of underlying fat and connective tissue. The additional growth takes place in a cyclic way, with certain regression occurring at the end of each cycle. Mammary gland development is under multihormonal control, involving functional interaction between the ovaries and the pituitary. The coordinated action of estrogen, progesterone, glucocorticoids. insulin, growth hormone and thyroid gland are involved. Traditional endocrine gland replacement studies show that ovarian estradiol is critical to the major phases of mammary development, ductal elongation during puberty and lobuloalveolar development during pregnancy. However, the effects of estrogens on mammary growth appeared requiring a functional pituitary gland. Therefore, estrogens may contribute to mammary development by acting directly on the mammary gland and or by indirect endocrine action of the hypothalamic/pituitary/gonadal axis. The alveolar development is also controlled by prolaction and progesterone; lactation is mediated by prolactin. Estrogen, as established before, is ineffective in the absence of anterior pituitary hormones. Administration of estrogens to animals promotes the formation if lactotropic cells in the pituitary increase the secretion of prolaction and growth hormone. In the presence of these two hormones, estrogen acts to promote ductal development in the breast. Although estrogen prepares the breast for eventual milk formation, it also acts to inhibit lactation and in to act as antagonist of prolactin. This happens mostly because of the high levels of circulating estrogen and progesterone, which circulate and make women not to lactate during pregnancy, as well as the abrupt withdrawal of these tow hormones which, with the termination of pregnancy, triggers the onset of lactation. Estrogen also acts to regulate the number of prolactin receptors in breast tissue. |
Phytoestrogens are a diverse group of components of the nonsteroidal plant that can behave as estrogens and occur naturally in most plants, fruits, and vegetables. They were first observed in 1926 due to having estrogenic activity, more specifically because of the position and the distance of the hydroxyl substitutes enabled the molecule to bind to estrogen receptors. The molecule binds both receptor types: the estrogen alpha and the estrogen Beta. Many phytoestrogens seems to have higher affinity for the ERB receptor than steroidal estrogens, which suggests that they may exert there actions through different paths. However, despite their ability to bind to the estrogen receptor, they are much weaker then than human estrogens, with 105 times less activity. Phytoestrogens are both alike, as well as their antiestrogenic activity. Whether they act as an estrogen or as an antiestrogen seems to depend on the amount of endogenous estrogens and the number and type of latest estrogen receptor, but not least the tissue type in which the receptors are expressed. Phytoestrogens are frequently detected in the man in much higher quantities than the produced endogenous estrogens. There are three main types of phytoestrogens: the isoflavones (the most potent), coumestrans, and lignans. There are more than 1000 types of isoflavones, but the most commonly investigated are genistein and daidzein, which are also thought to have the highest estrogenic activity. They are found in legumes such as soy, chickpeas, clover, lentils and beans. The isoflavones are bound to glucose and, when ingested by humans, they are enzymatically cleaved in the gut by the active forms. The metabolism of the phytoestrogens varies from person to person, and there also seems to be a sex difference because women metabolize them more efficiently. The lignans (enterolactone or enterodiol) are found in flaxseed, lentils, whole grains, beans fruits and vegetables. Other classes which are more rarely ingested are the coum (found in sprouting plants), flavones, flavanones, chalcones, terpenoids, and saponins. |
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HOME - HOW DOES IT WORK? - EXPECTED RESULTS - WHY ARE WE # 1? - MEDICAL COMMUNITY [ ProcurvesPlus.com ] "This product is not a medicine and does not expect to diagnose, prevent, treat or cure any disease or pain. The information in this website has been published for information purposes only and does not substitute a doctor’s advice. This product has not been evaluated by the Food and Drug Administration. If you have any illness or pain, please visit your doctor before using any product. Individual results may vary from person to person. Please read the product’s information and label very carefully before using it. The results are based in tests carried out by third parties, doctors’ recommendations and customers’ testimonies. The Procurves Program refers to Breast Performance exercises and Procurves pills, jointly."
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